Let’s be honest: Weight loss is hard. I totally understand that, and it has even been a personal struggle for me, too. That’s why I want to share a quick deep dive into one of my latest products: Metabolism Boost. We’ll discuss how this can be a metabolism booster for weight loss and how it can help guide you in a healthy direction.
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February 14, 2022Home > Weight Loss > Metabolism Boost: Giving Weight Loss A Real Boost
Metabolism Boost: Giving Weight Loss A Real Boost
Product Recommendation: The ingredients in Metabolism Boost have been clinically proven to increase basal metabolic rate with thyroid disease, lower appetite, break down stored liver fat, reduce the absorption of fat and carbohydrate. Click Here
Table of Contents
Are You Struggling With Weight Loss?
Thyroid Disease, Body Weight, and Weight Loss
How Does Thyroid Disease Cause Weight Gain?
How Do Weight Loss Supplements Work?
What Are The Benefits Of Metabolism Boost?
How Do You Take Metabolism Boost?
How Is Metabolism Boost Formulated?
How Do You Select Thyroid Specific Formulation Ingredients?
Metabolism Boost: Ingredients Breakdown
Supportive Strategies For Weight Loss
How Should You Take Metabolism Boost?
What Doesn’t Metabolism Boost Contain?
Resources
Are You Struggling With Weight Loss?
Weight loss is easily the number one concern I hear about from patients and readers alike. The fact is that a supplement can’t possibly lead to massive amounts of weight loss, it simply doesn’t work like that.
But, there is solid and reputable data showing that some supplements can help you get more results from your efforts. That’s why I handcrafted this product to be safe, effective, and to specifically address reasons for weight gain from thyroid disease.
In short, I’d like to consider it the perfect companion to the Metabolism Reset Diet. On top of that, though, it is also a good option to help keep hold of benefits throughout the maintenance phase. This way, your weight loss becomes sustainable and lasts the test of time.
So, what’s in it and how does it work? Here is all the detailed information that I provided for the product monograph — with more to come soon!
Thyroid Disease, Body Weight, and Weight Loss
Let’s consider a couple of the following data points to help frame today’s conversation:
“Among adults with body mass index scores greater than 30, as many as 60% may have autoimmune thyroid disease1.”
“Even in adults without overt thyroid disease, body weight and visceral fat relate to thyroid levels. A TSH change of 1 unit relates to weight changes of 0.66 pounds for women, and 1.8 pounds for men2.”
The fact is that weight loss resistance is the single most common symptom associated with thyroid disease. Some may even find that they never had any struggles with weight prior to the onset of thyroid disease.
Others find that thyroid disease now amplifies their already ongoing weight struggles. Either way, it is not ideal and it can be traced back to thyroid disease.
The specific symptoms here can include:
- Unexpected weight gain
- Weight loss only possible with extreme measures
- Inability to lose weight even with extreme measures
How Does Thyroid Disease Cause Weight Gain?
Your thyroid function can affect body weight for multiple reasons.
The primary mechanism is the relationship between thyroid function and basal metabolic rate (BMR). The BMR is the number of calories that the body burns through thermoregulation and maintaining homeostasis3.
It represents the largest source of energy expenditure by far for most adults.
Key Insight: When thyroid function is impaired, BMR can be 40% lower than it would be otherwise.
Thyroid function can also have effects on weight due to changes in fluid retention, sodium balance, non-exercise activity thermogenesis (NEAT), and preferences in exercise frequency and duration.
How Do Weight Loss Supplements Work?
Supplements may help weight loss efforts through a variety of different mechanisms.
Some mechanisms may not be safe or helpful when weight gain relates to thyroid disease. Others can be more appropriate. These include:
- Appetite Reduction – decreasing the amount of food preferred.
- Increase NEAT – raising the amount of energy expended through daily activities.
- Lower Inflammation – decreasing the number of inflammatory triggers and associated hormones like leptin and adiponectin.
- Amylase Blocker – decreasing the absorption of dietary starch.
- Lipase Blocker – decreasing the absorption of dietary fat.
- Increase Hepatic Lipogenesis – Improving the breakdown of stored fat from within the liver.
- Raise Diet-Induced Thermogenesis – Increasing the effect of meals on elevating the BMR.
What Are The Benefits Of Metabolism Boost?
With all that in mind, I set to work in creating a thyroid specific formulation that would take the shape of “Metabolism Boost.” But what are some of the benefits I keyed in on?
The ingredients in Metabolism Boost have been clinically proven to:
- Increase basal metabolic rate with thyroid disease
- Lower appetite
- Break down stored liver fat
- Reduce the absorption of fat and carbohydrate
How Do You Take Metabolism Boost?
All you have to do is take two pills, once daily, in the morning and with food. You should use Metabolism Boost in conjunction with a weight loss program.
How Is Metabolism Boost Formulated?
Metabolism Boost is comprised of the following:
- 400 mg of white kidney bean extract
- 300 mg of cayenne pepper fruit powder
- 250 mg of choline
- 100 mg of nigella
- 25 mg of magnesium
- 2 mg of zinc
How Do You Select Thyroid Specific Formulation Ingredients?
This is important. In this case, every single ingredient considered must share the following properties to warrant inclusion…
Thyroid Safety
All considered ingredients must be natural compounds that have been safely consumed by humans for centuries. They must be generally recognized as safe (GRAS) by toxicologists. Finally, they must not contain unsafe levels of iodine.
Evidence & Efficacy
All considered ingredients must have high-quality evidence proving their efficacy. The best quality evidence is that which demonstrates significant positive outcomes, on human subjects, in multiple, double-blinded controlled studies.
Ultimately, these human subjects and the outcomes should be clinically relevant to the product’s end-users. It needs to mean something for them.
Metabolism Boost: Ingredients Breakdown
So, now that you know a bit more about what went into Metabolism Boost, how do each of these ingredients help? Here, I’ve included their relevance to thyroid disease, mechanisms of action, and a review of supporting research…
White Kidney Bean Extract
White kidney beans (phaseolus vulgaris) are similar to the common cannellini bean and are a rich source of resistant starch.
Key Insight: Extracts of white kidney beans have been shown to slow the absorption of carbohydrates into the bloodstream.
A recent review of multiple clinical trials on white kidney bean extract (WKBE) showed that:
“This particular dietary supplement has demonstrated its potential and ability to cause weight loss in numerous clinical trials in humans4”
It also appears to help by lowering the activity of the enzyme amylase which breaks complex carbohydrates into simple carbohydrates. They also reduce the rate at which carbohydrates leave the stomach and enter the small intestines.
White kidney bean extract also seems to improve the gut microbiota. Some of these improvements have direct benefits to weight management, others can help the recovery of autoimmune diseases5.
In a typical study, 62 overweight and obese adults took a supplement containing white kidney bean extract, or a placebo, for nine months.
Compared to placebo, those taking white kidney bean extract experienced numerous health benefits including:
- Loss of body weight
- Loss of body fat
- A lower waist circumference
- Lower blood pressure
- Lower total cholesterol6
Cayenne Pepper Fruit Powder
Cayenne extract is taken from the fruit of the cayenne pepper plant. It is the source of cayenne pepper, the same you might find in your kitchen or on the dinner table!
In supplemental form it has been shown to have numerous properties helpful for weight loss including7:
- Suppressing appetite and inducing satiety
- Enhancing lipid metabolism
- Enhancing thermogenesis
- Inhibiting lipase and alpha-amylase
- Preventing adipocyte differentiation
Researchers who have reviewed the medical literature concluded that capsaicin can “Increase fat oxidation, improve insulin sensitivity, decrease body fat, and improve heart and liver function8.”
At low doses, capsaicin is well tolerated and can still exert the above weight loss benefits.
In a recent clinical trial, 103 overweight and obese adults were given a supplement containing cayenne pepper extract or a placebo9.
Compared to those on the placebo, those taking cayenne experienced:
- Higher quantities of fat loss
- Improved resting energy expenditure
- Reduced symptoms of depression
- Improved blood sugar metabolism
- Lower inflammation
Choline
Choline is a conditionally-essential nutrient chemically related to the B-Vitamins folate, pyridoxine, and B12. It can be synthesized by the body and found in dietary sources.
Many diets lack sufficient choline and many individuals are unable to metabolize the amounts they require. Thyroid disease has been shown to impair the body’s ability to produce choline10.
Choline is an essential nutrient related to the water-soluble B-complex vitamins, folate, pyridoxine, and B12, and to the essential amino acid, methionine. It is synthesized in the body as well as consumed in the diet.
In a double-blind human clinical trial, 21 female athletes were given supplements with choline or placebo for seven days. None were instructed to undergo dietary modifications.
Compared with those on placebo, those taking choline had lower leptin levels, saw a 3% reduction in body fat. These changes came without decreased strength or changes in performance11.
Nigella Sativa
Nigella sativa, also known as black cumin, is a culinary seed.
It has been used for thousands of years as a traditional medicine and source of cooking oil in the Middle East. Its main medical properties have been as an anti-inflammatory and immune regulator.
Key Insight: Since it has a long history of use as a food, nigella is considered safe for general usage over a wide range of dosages.
Evidence shows that Nigella helps weight loss through an improvement in the breakdown of fat within liver cells and an increase in insulin sensitivity by muscle cells. It also may act as a lipase inhibitor, lowering the absorption of fat from the diet.
Nigella is known to block the production of fatty acids. It is considered one of the strongest known botanical medications for reducing the formation of triglycerides (fats) and blocking lipase, the enzyme that forms them12.
In a recent clinical trial, people with thyroid disease were randomly distributed to receive a supplement containing either nigella or a placebo.
Those receiving nigella saw significant improvements in:
- Bodyweight
- Body mass index (BMI)
- Waist circumference
- Hip circumference
Despite the fact that there were no significant dietary differences between those taking nigella and those on placebo, none of these weight loss benefits were observed in participants in the placebo group13.
The beneficial effects of nigella appeared to be independent of any dietary changes.
Liver Support
Fatty liver is one of the main reasons for weight loss resistance with hypothyroidism.
In this condition, the liver cells have too much triglyceride relative to glycogen and are unable to burn fat. If the liver cannot process fat through beta oxidation, weight loss becomes more difficult and rapid weight regain is more likely.
Magnesium
Those with higher intakes of magnesium have lower odds of fatty liver and associated complications such as prediabetes14.
Zinc
Zinc deficiency is common among those with thyroid disease since many with thyroid disease also have autoimmune gastritis.
Low levels of zinc are known to contribute to several conditions including insulin resistance and advanced versions of fatty liver disease15.
Supportive Strategies For Weight Loss
So, alongside Metabolism Boost, what else can you do to realize your goals of weight loss? Here are some strategies that I can recommend which might help:
Let’s think of weight loss as happening in two distinct phases:
- Active weight loss
- Maintenance
Key Insight: Active weight loss should be limited to 4-5 week windows of time to prevent a reduction in the basal metabolic rate.
During weight loss, one should prioritize dietary protein and consume no less than one gram of protein per pound of lean body mass. Exercise should continue but should be limited to 20 minutes daily.
For detailed guidance on active weight loss, and even guidance on maintenance, I would recommend checking out a copy of the Metabolism Reset Diet today.
How Should You Take Metabolism Boost?
Two capsules, once daily, with food. In addition, make sure to take Metabolism Boost at least one hour after taking your thyroid medication.
What Doesn’t Metabolism Boost Contain?
Metabolism Boost does not contain any of the following:
- Caffeine
- Stimulants
- Thyroid hormones
- Iodine
- GMO
- Gluten
- Dairy
Try Metabolism Boost Today
Now that you know a bit more about it, how about trying it for yourself? If you’re interested in optimizing your metabolism and the process of weight loss, then Metabolism Boost may be perfect for you.
1 – Bernadette Biondi, Thyroid and Obesity: An Intriguing Relationship, The Journal of Clinical Endocrinology & Metabolism, Volume 95, Issue 8, 1 August 2010, Pages 3614–3617, https://doi.org/10.1210/jc.2010-1245
2 – Bjergved L, Jørgensen T, Perrild H, et al. Thyroid function and body weight: a community-based longitudinal study. PLoS One. 2014;9(4):e93515. Published 2014 Apr 11. doi:10.1371/journal.pone.0093515
3 – Min Joo Kim, Sun Wook Cho, Sumin Choi, Dal Lae Ju, Do Joon Park, Young Joo Park, “Changes in Body Compositions and Basal Metabolic Rates during Treatment of Graves’ Disease”, International Journal of Endocrinology, vol. 2018, Article ID 9863050, 8 pages, 2018. https://doi.org/10.1155/2018/9863050
4 – Udani J, Tan O, Molina J. Systematic Review and Meta-Analysis of a Proprietary Alpha-Amylase Inhibitor from White Bean (Phaseolus vulgaris L.) on Weight and Fat Loss in Humans. Foods. 2018;7(4):63. Published 2018 Apr 20. doi:10.3390/foods7040063
5 – Nolan R, Shannon OM, Robinson N, Joel A, Houghton D, Malcomson FC. It’s No Has Bean: A Review of the Effects of White Kidney Bean Extract on Body Composition and Metabolic Health. Nutrients. 2020;12(5):1398. Published 2020 May 13. doi:10.3390/nu12051398
6 – Birketvedt GS, Travis A, Langbakk B, Florholmen JR. Dietary supplementation with bean extract improves lipid profile in overweight and obese subjects. Nutrition. 2002 Sep;18(9):729-33. doi: 10.1016/s0899-9007(02)00831-6. PMID: 12297207.
7 – Narang N, Jiraungkoorskul W, Jamrus P. Current Understanding of Antiobesity Property of Capsaicin. Pharmacogn Rev. 2017;11(21):23-26. doi:10.4103/phrev.phrev_48_16
8 – Panchal SK, Bliss E, Brown L. Capsaicin in Metabolic Syndrome. Nutrients. 2018 May 17;10(5):630. doi: 10.3390/nu10050630. PMID: 29772784; PMCID: PMC5986509.
9 – Rondanelli, Mariangela et al. “Improvement in insulin resistance and favourable changes in plasma inflammatory adipokines after weight loss associated with two months’ consumption of a combination of bioactive food ingredients in overweight subjects.” Endocrine vol. 44,2 (2013): 391-401. doi:10.1007/s12020-012-9863-0
10 – Reduced myo-inositol and total choline measured with cerebral MRS in acute thyrotoxic Graves’ disease T.V. Elberling, E.R. Danielsen, Å.K. Rasmussen, U. Feldt-Rasmussen, G. Waldemar, C. Thomsen Neurology Jan 2003, 60 (1) 142-145; DOI: 10.1212/01.WNL.0000038911.07643.BF
11 – Elsawy G, Abdelrahman O, Hamza A. Effect of choline supplementation on rapid weight loss and biochemical variables among female taekwondo and judo athletes. J Hum Kinet. 2014;40:77-82. Published 2014 Apr 9. doi:10.2478/hukin-2014-0009
12 – Mollazadeh H, Mahdian D, Hosseinzadeh H. Medicinal plants in treatment of hypertriglyceridemia: A review based on their mechanisms and effectiveness. Phytomedicine. 2019 Feb;53:43-52. doi: 10.1016/j.phymed.2018.09.024. Epub 2018 Sep 5. PMID: 30668411.
13 – Farhangi MA, Dehghan P, Tajmiri S, Abbasi MM. The effects of Nigella sativa on thyroid function, serum Vascular Endothelial Growth Factor (VEGF) – 1, Nesfatin-1 and anthropometric features in patients with Hashimoto’s thyroiditis: a randomized controlled trial. BMC Complement Altern Med. 2016 Nov 16;16(1):471. doi: 10.1186/s12906-016-1432-2. PMID: 27852303; PMCID: PMC5112739.
14 – Li W, Zhu X, Song Y, Fan L, Wu L, Kabagambe EK, Hou L, Shrubsole MJ, Liu J, Dai Q. Intakes of magnesium, calcium and risk of fatty liver disease and prediabetes. Public Health Nutr. 2018 Aug;21(11):2088-2095. doi: 10.1017/S1368980018000642. Epub 2018 Apr 2. PMID: 29607802; PMCID: PMC6310058.
15 – Himoto T, Masaki T. Associations between Zinc Deficiency and Metabolic Abnormalities in Patients with Chronic Liver Disease. Nutrients. 2018;10(1):88. Published 2018 Jan 14. doi:10.3390/nu10010088
P.S. Whenever you are ready, here is how I can help you now:
1. Schedule a Thyroid Second Opinion with me, Dr. C, Click Here for Details
2. Need A Thyroid Supplement Recommendation? Take My Thyroid Specific Formulations Quiz Now
3. Need a Personalized Supplement? Check out My Thyroid Specific Formulations
4. Download and use my Favorite Recipes Cookbook Here
5. Check out my podcast Medical Myths, Legends, and Fairytales Here
Dr. Alan Glen Christianson (Dr. C) is a Naturopathic Endocrinologist and the author of The NY Times bestselling Adrenal Reset Diet, The Metabolism Reset Diet and The Thyroid Reset Diet.
Dr. C’s gift for figuring out what really works has helped hundreds of thousands of people reverse thyroid disease, lose weight, diabetes, and regain energy. Learn more about the surprising story that started his quest.
Dr. Alan Christianson
Alan Christianson is a Naturopathic Medical Doctor (NMD) who is a board-certified Naturopathic Endocrinologist with a focus on thyroid disorders. He is the author of The Metabolism Reset Diet and the New York Times bestselling book The Adrenal Reset Diet.
He founded Integrative Health, a physician group dedicated to helping people with thyroid disease and weight-loss resistance regain their health.
He has been named a Top Doctor in Phoenix magazine and has appeared on national TV shows and in numerous print media.
Dr. Christianson resides in the woods by a lake in Northern Minnesota with his wife Kirin.